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Postdoctoral Fellow - Shih Lab

About City of Hope


City of Hope, an innovative biomedical research, treatment and educational institution with over 4000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy. Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation???s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.


Requisition 14263


Job Title: Postdoctoral Fellowship - Cell Signaling of Pancreatic Beta-Cell Development and Maturation


Position Summary and Key Responsibilities:


A Postdoctoral Fellow position is available in the laboratory of Dr. Shih, at the Diabetes and Metabolism Research Institute (https://www.cityofhope.org/research/diabetes-metabolism-research-institute) at City of Hope. We are looking for a highly motivated postdoctoral fellow interested in studying the cell signaling regulation of pancreatic development and beta-cell maturation in animal models, as wells as stem-cell based systems. In addition, our lab is interested in studying the cell-environment and cell-cell interaction in fetal and neonatal pancreas development. The lab utilizes genetic mouse models, stem cell biology and imaging techniques to study the cellular identity, function, remodeling, and maturation of beta-cells during development and adult maintenance.


The specific research projects currently available in the lab are directed at determining: the role of environmental cues in controlling pancreas development. The functional requirement cell-cell interaction in maintaining beta-cell function.


The ideal candidate will have extensive experience in molecular biology and cell or developmental biology. Experience with histology/imaging techniques and rodent models preferred.?? The candidate should be self-motivated, with a proven track record of productivity. To apply, please send a cover letter stating your research interests and experience along with a curriculum vitae and the names of three references to Dr. Ben Shih: hshih@coh.org.


Minimum Education and Skills Required for Consideration:




  • PhD in Molecular, Cellular or Developmental Biology.


  • Strong interest in diabetes research/regenerative biology.


  • Extensive experience with basic molecular biology skills.


  • Experience in handling animal models preferred.


  • Experience with epigenetic techniques preferred.


  • Experience with tissue collection, histology and immunohistochemistry.


  • Experience with cell culture, immunofluorescence, flow cytometry, and cell-sorting.


  • Strong work ethic.


  • Excellent written and verbal communication skills. Evidence of productivity reflected in first author publications in peer-reviewed journals.


  • Good problem solving skills and passion to follow relevant literature.


  • Ability to conduct independent research, and work effectively in a team.



City of Hope is an equal opportunity employer.?? All qualified applicants will receive consideration for employment without regard to race, religion, color national origin, sex, age, status as a protected veteran, or status as a qualified individual with disability.




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